About RPAH

The Research Center of Methodology in Producing Active Ingredients from Cannabis and Herbs by Bioreactor (RPAH) is financially supported by APA Industries Co., Ltd., a prominent leader in primary packaging for pharmaceutical and cosmetic industries in Thailand. This center, established in collaboration with Payap University, a leading private institution in northern Thailand, officially commenced its activities with a memorandum of understanding (MOU) signing ceremony in 2022, followed by an inauguration ceremony on March 27, 2023.

RPAH's primary objective is to conduct research in various areas including tissue culture, bioreactor technology, active ingredient extraction, physiology, plasma technology, nanotechnology, and the processing of hemp, cannabis, and other economically valuable medicinal plants and herbs. The research aims to benefit pharmaceutical applications as well as products for everyday wellness, health care, food, supplements, beverages, and cosmetics, contributing to modern healthy living for humans and pets alike.

RPAH has focused on developing four key technologies to support industries throughout the production chain, from upstream to downstream. Addressing upstream challenges, traditional methods of cannabis active ingredient production have been hindered by factors such as genetic variations, environmental conditions, pests, and diseases. To address these limitations, RPAH employs bioreactors for the production of cannabis active ingredients. This technology, known as Callus for Essential Substances (CES-TECH), cultivates cannabis callus cells under controlled and sterile conditions, sourced from selected hemp varieties based on their specific properties.

A spinoff project, Cultivation Technology (RPAH-1), has been devised to enhance plant growth, particularly in increasing the yield of hemp fiber, seeds, and flowers. This technology can be applied across various cultivation methods, benefiting farmers and growers alike.

Moving to the midstream phase, RPAH has developed the Pulse Electric Field & Ultrasonic combined technologies (PEFUS) for efficient extraction of cannabis, hemp, and other medicinal plants. This innovation aims to produce high-quality medical-grade oils with minimal energy consumption and short processing times, aligning with clean, green, and zero-waste principles.

Furthermore, RPAH has introduced the Tetrahydroxy Elimination Technique (THET), a technology aimed at transforming THC into CBN (Cannabinol). CBN is recognized for its potential benefits in promoting relaxation, improving sleep quality, and providing relief from chronic pain and inflammation.

In the downstream phase, RPAH collaborates with renowned institutes and universities to develop everyday wellness and healthcare products. These initiatives aim to advance modern healthy living by researching effective solutions and developing useful medicines.